BDNF Protein 248-BDB-050/CF from R&D Systems, a Bio-Techne Brand

Product Specs
ItemBDNF Protein
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number248-BDB-050/CF
Quantity50 ug (also 10 ug, 250 ug, 1 mg)
ApplicationsBioactivity
Conjugate/TagUnconjugated
Purity>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining
Molecular WeightObserved: 13-14 kDa, under reducing conditions.
Theoretical: 13.5 kDa
SpeciesHuman, Mouse, Rat, Canine, Equine
Molecule NameBDNF
Brand/TrademarkR&D Systems, a Bio-Techne Brand
NCBI Full Gene Namebrain derived neurotrophic factor
NCBI Gene AliasesBULN2, ANON2
FormatLyophilized from a 0.2 µm filtered solution in Sodium Citrate and NaCl
Source/Expression SystemSf 21 (baculovirus)-derived Recombinant Human BDNF Protein
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, <= -20 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasisAutophagyJuly 1, 2023Jun YW, Lee S, Ban BK, Lee JA, Gao FB.

(2) VEGFA-modified DPSCs combined with LC-YE-PLGA NGCs promote facial nerve injury repair in ratsHeliyonApril 1, 2023Xu W, Xu X, Yao L, Xue B, Xi H, Cao X, Piao G, Lin S, Wang X.

(3) hPSC-derived sacral neural crest enables rescue in a severe model of Hirschsprung's diseaseCell stem cellMarch 2, 2023Fan Y, Hackland J, Baggiolini A, Hung LY, Zhao H, Zumbo P, Oberst P, Minotti AP, Hergenreder E, Najjar S, et al.

(4) Pervasive environmental chemicals impair oligodendrocyte developmentbioRxiv : the preprint server for biologyFebruary 12, 2023Cohn EF, Clayton BLL, Madhavan M, Yacoub S, Federov Y, Paul-Friedman K, Shafer TJ, Tesar PJ.

(5) Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neuronsCell stem cellFebruary 2, 2023Álvarez Z, Ortega JA, Sato K, Sasselli IR, Kolberg-Edelbrock AN, Qiu R, Marshall KA, Nguyen TP, Smith CS, Quinlan KA, et al.

(6) SYF2 suppression mitigates neurodegeneration in models of diverse forms of ALSCell stem cellFebruary 2, 2023Linares GR, Li Y, Chang WH, Rubin-Sigler J, Mendonca S, Hong S, Eoh Y, Guo W, Huang YH, Chang J, et al.

(7) Astrocytic cell adhesion genes linked to schizophrenia correlate with synaptic programs in neuronsCell reportsJanuary 31, 2023Pietiläinen O, Trehan A, Meyer D, Mitchell J, Tegtmeyer M, Valakh V, Gebre H, Chen T, Vartiainen E, Farhi SL, et al.

(8) Increased post-mitotic senescence in aged human neurons is a pathological feature of Alzheimer's diseaseCell stem cellDecember 1, 2022Herdy JR, Traxler L, Agarwal RK, Karbacher L, Schlachetzki JCM, Boehnke L, Zangwill D, Galasko D, Glass CK, Mertens J, et al.

(9) A reference human induced pluripotent stem cell line for large-scale collaborative studiesCell stem cellDecember 1, 2022Pantazis CB, Yang A, Lara E, McDonough JA, Blauwendraat C, Peng L, Oguro H, Kanaujiya J, Zou J, Sebesta D, et al.(Life Technologies; 35050-038), 1x PenStrep (Life Technologies; 15140-122), 10 ng/mL BDNF (R&D Systems; 248-BDB-050/CF), 10 ng/mL GDNF (R&D Systems; 212-GD-010), 200 μM ascorbic acid, 0.5 mM dbcAMP (Sigma-Aldrich), 10 μM

(10) Norepinephrine transporter defects lead to sympathetic hyperactivity in Familial Dysautonomia modelsNature communicationsNovember 17, 2022Wu HF, Yu W, Saito-Diaz K, Huang CW, Carey J, Lefcort F, Hart GW, Liu HX, Zeltner N.

(11) Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expressionNature neuroscienceNovember 1, 2022Seah C, Breen MS, Rusielewicz T, Bader HN, Xu C, Hunter CJ, McCarthy B, Deans PJM, Chattopadhyay M, Goldberg J, et al.

(12) Genome-wide CRISPR screen reveals v-ATPase as a drug target to lower levels of ALS protein ataxin-2Cell reportsOctober 25, 2022Kim G, Nakayama L, Blum JA, Akiyama T, Boeynaems S, Chakraborty M, Couthouis J, Tassoni-Tsuchida E, Rodriguez CM, Bassik MC, et al.

(13) Generation and characterization of motor neuron progenitors and motor neurons using metachromatic leukodystrophy-induced pluripotent stem cellsMolecular genetics and metabolism reportsJune 1, 2022Hossain MA, Hasegawa-Ogawa M, Manome Y, Igarashi M, Wu C, Suzuki K, Igarashi J, Iwamoto T, Okano HJ, Eto Y.

(14) Astrocytic BDNF signaling within the ventromedial hypothalamus regulates energy homeostasisNature MetabolismMay 2, 2022Dominique Ameroso, Alice Meng, Stella Chen, Jennifer Felsted, Chris G. Dulla, Maribel Riossingle i.c.v. injection into their lateral ventricle of either 4 uL aCSF or 2.5 ug BDNF (R&D Systems, 248-BDB-050/CF) diluted in aCSF. Stereotaxic coordinates used to target the lateral ventricle were A/P −0.22, M/L +

(15) Human Neurons Form Axon-Mediated Functional Connections with Human Cardiomyocytes in Compartmentalized Microfluidic ChipInternational journal of molecular sciencesMarch 15, 2022Häkli M, Jäntti S, Joki T, Sukki L, Tornberg K, Aalto-Setälä K, Kallio P, Pekkanen-Mattila M, Narkilahti S.

(16) A combined cell and gene therapy approach for homotopic reconstruction of midbrain dopamine pathways using human pluripotent stem cellsCell stem cellMarch 3, 2022Moriarty N, Gantner CW, Hunt CPJ, Ermine CM, Frausin S, Viventi S, Ovchinnikov DA, Kirik D, Parish CL, Thompson LH.

(17) Phoenix auditory neurons as 3R cell model for high throughput screening of neurogenic compoundsHearing researchFebruary 1, 2022Rousset F, Schmidbauer D, Fink S, Adel Y, Obexer B, Müller M, Glueckert R, Löwenheim H, Senn P.

(18) Human Sensory Neuron-like Cells and Glycated Collagen Matrix as a Model for the Screening of Analgesic CompoundsCellsJanuary 12, 2022Bufalo MC, Almeida MES, Jensen JR, DeOcesano-Pereira C, Lichtenstein F, Picolo G, Chudzinski-Tavassi AM, Sampaio SC, Cury Y, Zambelli VO.

(19) Pharmacotherapy alleviates pathological changes in human direct reprogrammed neuronal cell model of myotonic dystrophy type 1PloS oneJanuary 1, 2022Eltahir MK, Nakamori M, Hattori S, Kimura T, Mochizuki H, Nagano S.

(20) G2019S LRRK2 Mutation Enhances MPP(+)-Induced Inflammation of Human Induced Pluripotent Stem Cells-Differentiated Dopaminergic NeuronsFrontiers in neuroscienceJanuary 1, 2022Chen Y, Yin Q, Cheng XY, Zhang JR, Jin H, Li K, Mao CJ, Wang F, Bei HZ, Liu CF.

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BDNF Protein

BDNF Protein

BDNF Protein

BDNF Protein

BDNF Protein

BDNF Protein from R&D Systems, a Bio-Techne Brand

Description

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (222)

Reviews

BDNF Protein from R&D Systems, a Bio-Techne Brand

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