Soluble Epoxide Hydrolase (human, recombinant) 10011669 from Cayman Chemical

Product Specs
ItemSoluble Epoxide Hydrolase (human, recombinant)
CompanyCayman Chemical
Price $439.00Supplier Page View Company Product Page
Catalog Number10011669
Size50 µg
Specieshuman
Source/Expression SystemInsect cells
NCBI Full Gene Nameepoxide hydrolase 2
NCBI Gene AliasesABHD20, CEH, SEH
Research AreaAlzheimer’s Disease, Arthritis (Non-Autoimmune), Atherosclerosis, Cardiovascular Diseases, Cardiovascular System, Cytochrome P450 Pathways, Endocrinology & Metabolism, Gastric Disease, Heart, Hypertension, Immunology & Inflammation, Kidney & Renal Disease, Lipid Biochemistry, Neurodegenerative Disorders, Neuroprotection, Neuroscience, Pain Research, Reproductive Biology, Seizure Disorders, Stroke, Vasculature
Molecular Weight64 kDa
Purity≥95% estimated by SDS-PAGE
FormatTBS, pH 7.4, with 20% glycerol
Storage-80
OriginUSA

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Soluble epoxide hydrolase inhibitory constituents from the Heartwood of Toxicodendron vernicifluum: isolation, kinetic characterization, molecular modeling, and quantitative analysisScientific ReportsJanuary 20, 2026Jang Hoon Kim, Jae-Young Cheon, Jin Yu, Yong-Goo Kim, Sung Yeon Kim, Kyong-Hwan Bang, Jin Tae Jeong, Hyun-Ju Jung, Ik Soo Leeanalytical grade formic acid was purchased from Merck (St. Louis, MO, USA). Human recombinant sEH (10011669), PHOME (10009134), and AUDA (10007972) were from Cayman Chemical (Ann Arbor, MI, USA). Plant material T.

(2) Indirubin-3'-oxime as a dual-action agent: mitigating heat-induced male infertility in Drosophila melanogaster and inhibiting soluble epoxide hydrolaseJ Enzyme Inhib Med ChemJanuary 22, 2025Nguyen Viet Phong, Hyo-Sung Kim, Yan Zhao, Eunbyul Yeom, Seo Young Yangbuffer (B9754) were purchased from Sigma-Aldrich (St. Louis, MO). sEH (human, recombinant; Item No. 10011669), PHOME (Item No. 10009134), and AUDA (Item No. 10007927) were purchased from Cayman Chemical (Ann Arbor,

(3) Intradomain Allosteric Regulation of Soluble Epoxide Hydrolase by Its SubstratesInternational Journal of Molecular SciencesDecember 17, 2024Shin Matsumura, Ayano Shida, Moeno Tsuchii, Mika Wada, Jimmy Charneau, Motonori Tsuji, Keiji Hasumi, Eriko SuzukiMaterials and Methods 4.1. Materials Recombinant human sEH (N-terminal His-tagged protein; item No. 10011669) was purchased from Cayman Chemical (Ann Arbor, MI, USA). The N-phos substrate AttoPhos was obtained

(4) Inhibitory Activity of Glycosides from Elsholtzia ciliata against Soluble Epoxide Hydrolase and Cytokines in RAW264.7 CellsJournal of Microbiology and BiotechnologyNovember 11, 2024Jang Hoon Kim, Ji Hyeon Park, Kyung-Sook Han, Eun-Song Lee, Yong-Goo Kim, Yong-Il Kim, Sung Cheol Koo, Byoung Ok Chopolyinosinic–polycytidylic acid sodium salt (poly(I:C)) were obtained from Merck and human recombinant sEH (10011669), 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methyl ester-2-oxiraneacetic acid (PHOME, 10009134), and AUDA

(5) Inhibition of Soluble Epoxide Hydrolase by Cembranoid Diterpenes from Soft Coral Sinularia maxima: Enzyme Kinetics, Molecular Docking, and Molecular DynamicsMarine DrugsAugust 17, 2024Nguyen Viet Phong, Nguyen Phuong Thao, Le Ba Vinh, Bui Thi Thuy Luyen, Chau Van Minh, Seo Young YangMaterials, Institute of Marine Biochemistry, VAST. 4.2. Chemicals and Reagents sEH (human, recombinant; 10011669), PHOME (10009134), and AUDA (10007927) were purchased from Cayman Chemical (Ann Arbor, MI, USA). Bis-Tris

(6) The Inhibition Activity of Natural Methoxyflavonoid from Inula britannica on Soluble Epoxide Hydrolase and NO Production in RAW264.7 CellsInternational Journal of Molecular SciencesApril 15, 2024Jang Hoon Kim, Kyung-Sook Han, Eun-Song Lee, Yong-Goo Kim, Yong-Il Kim, Byoung Ok Cho, Ik Soo Leealbumin (BSA, A8806) were purchased from Sigma-Aldrich (St. Louis, MO, USA), and human recombinant sEH (10011669), 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methyl ester-2-oxiraneacetic acid (PHOME, 10009134), and AUDA

(7) Inhibitory Activity of Natural cis-Khellactone on Soluble Epoxide Hydrolase and Proinflammatory Cytokine Production in Lipopolysaccharides-Stimulated RAW264.7 CellsPlants (Basel)October 23, 2023Jang Hoon Kim, Ji Hyeon Park, Sung Cheol Koo, Yun-Chan Huh, Mok Hur, Woo Tae Park, Youn-Ho Moon, Tae Il Kim, Byoung Ok Chofrom the professional reagent store (Sigma-Aldrich, St. Louis, MO, USA). Mammalian recombinant sEH (10011669), PHOME (10009134), and AUDA (10007972) were sourced from Cayman Chemical (Ann Arbor, MI, USA). The

(8) Anti-inflammatory of disenecionyl cis-khellactone in LPS-stimulated RAW264.7 cells and the its inhibitory activity on soluble epoxide hydrolaseHeliyonOctober 1, 2023Park JH, Kim JH, Jang SI, Cho BO.purchased from Invitrogen, Inc.(Waltham, MA, USA). Human recombinant soluble epoxide hydrolase (sEH, 10011669), cyano-(6-methoxynaphthalen-2-yl)methyl] 2-(3-phenyloxiran-2-yl)acetate (PHOME, 10009134), and 12-(3-((3s,5s,7s)-adamantan-1-yl)ureido)dodecanoic

(9) Inhibitory activity of lignanamides isolated from hemp seed hulls(Cannabis sativa L.) against soluble epoxide hydrolaseHeliyonSeptember 14, 2023Jang Hoon Kim, Yun-Chan Huh, Mok Hur, Woo Tae Park, Youn-Ho Moon, Tae IL. Kim, Seon Mi Kim, Sung-Cheol Koo(B9754) and bovine serum albumin (BSA) (A8806) were achieved at Sigma-Aldrich (St. Louis, MO, USA). sEH (10011669), 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methyl ester-2-oxiraneacetic acid (PHOME, 10009134), and positive

(10) Inhibition of Soluble Epoxide Hydrolase Activity by Components of Glycyrrhiza uralensisInternational Journal of Molecular SciencesMarch 30, 2023Jang Hoon Kim, Yun-Chan Huh, Mok Hur, Woo Tae Park, Youn-Ho Moon, Tae Il Kim, Yong Il Kim, Seon Mi Kim, Jeonghoon Lee, Ik Soo Leealbumin (BSA) (A8806) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Human recombinant sEH (10011669), PHOME (10009134), and AUDA (10007972) were purchased from Cayman Chemical (Ann Arbor, MI, USA). 4.2.

(11) Structure-activity relationship studies of benzothiazole-phenyl analogs as multi-target ligands to alleviate pain without affecting normal behaviorProstaglandins & Other Lipid MediatorsFebruary 1, 2023Jeannes Angelia, Xiaohui Weng, Aleksei Solomatov, Christopher Chin, Alyssa Fernandez, Paula K. Hudson, Christophe Morisseau, Bruce D. Hammock, Ram Kandasamy, Stevan Pecicrecombinant FAAH enzyme (Item No. 100101183, Batch No. 0523867) and human recombinant sEH enzyme (Item No. 10011669) was obtained from Cayman Chemical. Fig. 1 was created with BioRender.com. Molecular modeling studies

(12) Inhibitory Activity of Quaternary Isoquinoline Alkaloids on Soluble Epoxide HydrolaseCurrent Issues in Molecular BiologySeptember 16, 2022Jang Hoon Kim, Chong Woon Cho, Mok Hur, Woo Tae Park, Youn-Ho Moon, Sung-Cheol Koo, Yun-Chan Hur, Jong Seong Kang, Ik Soo LeeJatrorrhizine chloride (6681-15-8) was purchased from Aba Chem Scene (Monmouth Junction, NJ, USA). sEH (10011669), AUDA (479413-70-2), and 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methyl ester-2-oxiraneacetic acid

(13) Machine Learning on DNA-Encoded Library Count Data Using an Uncertainty-Aware Probabilistic Loss FunctionJournal of Chemical Information and ModelingMay 23, 2022Katherine S. Lim, Andrew G. Reidenbach, Bruce K. Hua, Jeremy W. Mason, Christopher J. Gerry, Paul A. Clemons, Connor W. ColeyKingFisher Duo Prime (ThermoFisher Scientific). CAIX (R&D Systems 2188-CA-010), sEH (Cayman Chemical 10011669–50), and SIRT2 (Cayman Chemical 20011191–100) were purchased from commercial vendors. Each protein was

(14) Facile synthesis of the fungus-derived natural products: N,N′-dipalmitoleyl urea (C16:1) and N,N′-dioleyl urea (C18:1)Natural Product ResearchApril 18, 2022Jozef Stec, Stevan PecicEnzyme Screening Assay Human recombinant FAAH enzyme (Item No. 100101183, Batch No. 0523867) (Item No. 10011669) was obtained from Cayman Chemical. Measurement of FAAH potency was performed using the substrate N-(6-methoxypyridin-3-yl)

(15) Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitorsBioorganic & medicinal chemistryDecember 1, 2021Wilt S, Kodani S, Valencia L, Hudson PK, Sanchez S, Quintana T, Morisseau C, Hammock BD, Kandasamy R, Pecic S.recombinant FAAH enzyme (Item No. 100101183, Batch No. 0523867) and human recombinant sEH enzyme (Item No. 10011669) were obtained from Cayman Chemical. Fig. 1 was created with BioRender.com. Molecular modeling studies

(16) Inhibition of soluble epoxide hydrolase by phytochemical constituents of the root bark of Ulmus davidiana var. japonicaJournal of Enzyme Inhibition and Medicinal ChemistryMay 18, 2021Jang Hoon Kim, Ji Su Park, Yun Ji Lee, Sena Choi, Young Ho Kim, Seo Young Yang(ODS-A 12 nm S-150, S-75 μm; YMC Co., Kyoto, Japan) were used for open column chromatography. sEH (10011669), AUDA (479413–70-2), and PHOME (10009134) were purchased from Cayman (Ann Arbour, Michigan, MO). Plant

(17) In Vitro and In Silico Studies of Soluble Epoxide Hydrolase Inhibitors from the Roots of Lycopus lucidusPlants (Basel)February 13, 2021Yoo Kyong Han, Ji Sun Lee, Seo Young Yang, Ki Yong Lee, Young Ho Kimn-hexane, CHCl3, EtOAc, n-BuOH, were purchased from SK chemical (Suwon, Gyeonggi-do, Korea). AUDA, sEH (10011669) and PHOME (10009134) were purchased from Cayman (Cayman, MI, USA.). 3.2. Plant Material The dried

(18) Development of multitarget inhibitors for the treatment of pain: Design, synthesis, biological evaluation and molecular modeling studiesBioorganic ChemistryOctober 1, 2020Stephanie Wilt et al.recombinant FAAH enzyme (Item No. 100101183, Batch No. 0523867) and human recombinant sEH enzyme (Item No. 10011669) were obtained from Cayman Chemical. Molecular modeling studies and docking experiments were performed

(19) Inhibitory Activity of Quercetin 3-O-Arabinofuranoside and 2-Oxopomolic Acid Derived from Malus domestica on Soluble Epoxide HydrolaseMoleculesSeptember 22, 2020In Sook Cho, Jang Hoon Kim, Yunjia Lin, Xiang Dong Su, Jong Seong Kang, Seo Young Yang, Young Ho Kim500 spectrometer (1 H, 500 MHz and 13 C, 125 MHz) (Tokyo, Japan). AUDA (10007927), soluble epoxide hydrolase (10011669), and 3-phenyl-cyano(6-methoxy-2-naphthalenyl) methyl ester-2-oxiraneacetic acid (PHOME) (10009134)

(20) Coumarin and Moracin Derivatives from Mulberry Leaves (Morus alba L.) with Soluble Epoxide Hydrolase Inhibitory ActivityMoleculesAugust 31, 2020Hong Xu Li, Myungsook Heo, Younghoon Go, Young Soo Kim, Young Ho Kim, Seo Young Yang, Wei Lipurchased from Sigma Aldrich (St. Louis, MO, USA). Human recombinant soluble epoxide hydrolases (sEH, 10011669), and 3-phenyl-cyano(6-methoxy-2-naphthalenyl)methyl ester-2-oxiraneacetic acid (PHOME) (10009134) were

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Soluble Epoxide Hydrolase (human, recombinant)

Soluble Epoxide Hydrolase (human, recombinant)

Soluble Epoxide Hydrolase (human, recombinant)

Soluble Epoxide Hydrolase (human, recombinant) from Cayman Chemical

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Cayman Chemical

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Soluble Epoxide Hydrolase (human, recombinant) from Cayman Chemical

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