FGF basic/FGF2/bFGF (145 aa), Tissue Culture Grade Protein 4114-TC-01M from R&D Systems, a Bio-Techne Brand

Product Specs
ItemFGF basic/FGF2/bFGF (145 aa), Tissue Culture Grade Protein
CompanyR&D Systems, a Bio-Techne Brand
Price Pricing Info Supplier Page View Company Product Page
Catalog Number4114-TC-01M
SpeciesHuman
FormatLyophilized from a 0.2 µm filtered solution in Tris-HCl and NaCl
Molecule NameFGF basic/FGF2/bFGF
Quantity1 mg
NCBI Full Gene Namefibroblast growth factor 2
NCBI Gene AliasesFGFB, HBGF-2, FGF-2, BFGF
Molecular Weight16 kDa
Brand/TrademarkR&D Systems, a Bio-Techne Brand
Conjugate/TagUnconjugated
ApplicationsBioactivity
Source/Expression SystemE. coli-derived Recombinant Human FGF basic/FGF2/bFGF 145 aa TC Grade
StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution

Specifications/Features

Available conjugates: Unconjugated

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R&D Systems, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956

Fax: 1 (612) 656-4400

Company Profile

Website: http://www.rndsystems.com

(1) Cross-talk between PARN and EGFR-STAT3 Signaling Facilitates Self-Renewal and Proliferation of Glioblastoma Stem CellsCancer researchNovember 15, 2023Yin J, Seo Y, Rhim J, Jin X, Kim TH, Kim SS, Hong JH, Gwak HS, Yoo H, Park JB, et al.

(2) Breast cancer PDxO cultures for drug discovery and functional precision oncologySTAR ProtocolsSeptember 1, 2023Sandra D. Scherer, Ling Zhao, Andrew J. Butterfield, Chieh-Hsiang Yang, Emilio Cortes-Sanchez, Katrin P. Guillen, Bryan E. Welm, Alana L. Welm25-533 Human EGF,Sigma-Aldrich,cat# E9644 Y-27632,Selleck Chemicals,cat# S1069 FGF2,R&D Systems,cat# 4114-TC-01M N-Acetyl-L-Cysteine (NAC),Sigma-Aldrich,cat# A7250 Heregulin-β1 (NRG),Peprotech,cat# 100-03 TrypLE

(3) Regulation of Primary Cilium Length by O-GlcNAc during Neuronal Development in a Human Neuron ModelCellsMay 31, 2023Tian JL, Huang CW, Eslami F, Mannino MP, Mai RL, Hart GW.

(4) Lysine catabolism reprograms tumour immunity through histone crotonylationNatureMay 1, 2023Yuan H, Wu X, Wu Q, Chatoff A, Megill E, Gao J, Huang T, Duan T, Yang K, Jin C, et al.

(5) The oncogenic JAG1 intracellular domain is a transcriptional cofactor that acts in concert with DDX17/SMAD3/TGIF2Cell reportsNovember 22, 2022Kim EJ, Kim JY, Kim SO, Hong N, Choi SH, Park MG, Jang J, Ham SW, Seo S, Lee SY, et al.

(6) Convergent cerebrospinal fluid proteomes and metabolic ontologies in humans and animal models of Rett syndromeiScienceSeptember 16, 2022Zlatic SA, Duong D, Gadalla KKE, Murage B, Ping L, Shah R, Fink JJ, Khwaja O, Swanson LC, Sahin M, et al.12634-010) with N2 (Gibco 17502048), 2 mM L-glutamine (Sigma G7513), and 40 ng/mL beta-FGF (R&D Systems 4114-TC-01M). After 24 h, media was changed to differentiation media (Advanced DMEM/F12 with N2, 2 mM L-glutamine,

(7) Alpha synuclein determines ferroptosis sensitivity in dopaminergic neurons via modulation of ether-phospholipid membrane compositionCell reportsAugust 23, 2022Mahoney-Sanchez L, Bouchaoui H, Boussaad I, Jonneaux A, Timmerman K, Berdeaux O, Ayton S, Krüger R, Duce JA, Devos D, et al.

(8) Sox9 directs divergent epigenomic states in brain tumor subtypesProceedings of the National Academy of Sciences of the United States of AmericaJuly 19, 2022Sardar D, Chen HC, Reyes A, Varadharajan S, Jain A, Mohila C, Curry R, Lozzi B, Rajendran K, Cervantes A, et al.

(9) PDGF signaling inhibits mitophagy in glioblastoma stem cells through N(6)-methyladenosineDevelopmental cellJune 20, 2022Lv D, Gimple RC, Zhong C, Wu Q, Yang K, Prager BC, Godugu B, Qiu Z, Zhao L, Zhang G, et al.Proteins" Recombinant Human EGF,R&D Systems,Cat#236-EG-01M Recombinant Human FGF,R&D Systems,Cat#4114-TC-01M Recombinant Human PDGF-AA,R&D Systems,Cat#221-AA Recombinant Human PDGF-BB,R&D Systems,Cat#220-BB Recombinant

(10) Expanding homogeneous culture of human primordial germ cell-like cells maintaining germline features without serum or feeder layersStem cell reportsMarch 8, 2022Kobayashi M, Kobayashi M, Odajima J, Shioda K, Hwang YS, Sasaki K, Chatterjee P, Kramme C, Kohman RE, Church GM, et al.

(11) Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem CellsCancer DiscoveryFebruary 1, 2022Zhixin Qiu et al.growth factor (EGF) (R&D system Cat# 236-EG-01M) and recombinant human FGF basic (FGF) (R&D system Cat#4114-TC-01M) for a short period before treatment and analysis (7,59) . During routine culture, all GSC models were

(12) Autophagy and protein aggregation as a mechanism of dopaminergic degeneration in a primary human dopaminergic neuronal modelToxicology reportsJanuary 1, 2022Cuevas E, Guzman A, Burks SM, Ramirez-Lee A, Ali SF, Imam SZ.

(13) Optical tissue clearing and machine learning can precisely characterize extravasation and blood vessel architecture in brain tumorsCommunications BiologyDecember 1, 2021Serhii Kostrikov et al.growth factor (20 ng/ml, R&D systems, #236-EG-01M), fibroblast growth factors (20 ng/ml, R&D systems, #4114-TC-01M), GlutaMAX (Thermo Fisher Scientific, #35050-038), and antibiotics (Thermo Fisher Scientific, #15140122).

(14) Pharmacological inhibition of BACE1 suppresses glioblastoma growth by stimulating macrophage phagocytosis of tumor cellsNature CancerNovember 1, 2021Kui Zhai, Zhi Huang, Qian Huang, Weiwei Tao, Xiaoguang Fang, Aili Zhang, Xiaoxia Li, George R. Stark, Thomas A. Hamilton, Shideng Bao1150-04-100), human M-CSF (Biolegend, 574806), human IL-3 (Biolegend, 578006), and human bFGF (R&D Systems, 4114-TC-01M). Recombinant human SCF (300-07), VEGF (100-20), IL-4 (200-04), IL-6 (200-06), IL-10 (200-10), sIL-6R

(15) Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoidsNature communicationsAugust 5, 2021Cho AN, Jin Y, An Y, Kim J, Choi YS, Lee JS, Kim J, Choi WY, Koo DJ, Yu W, et al.β-mercaptoethanol (#63689-25ML-F; Sigma-Aldrich), and 10 ng/ml basic fibroblast growth factor (bFGF, #4114-TC-01M; R&D System Inc., Minneapolis, MN, USA). The cells were maintained on the feeder cell layers of 10 μg/ml

(16) Tanc2-mediated mTOR inhibition balances mTORC1/2 signaling in the developing mouse brain and human neuronsNature communicationsMay 11, 2021Kim SG, Lee S, Kim Y, Park J, Woo D, Kim D, Li Y, Shin W, Kang H, Yook C, et al.

(17) SLC6A20 transporter: a novel regulator of brain glycine homeostasis and NMDAR functionEMBO molecular medicineFebruary 5, 2021Bae M, Roh JD, Kim Y, Kim SS, Han HM, Yang E, Kang H, Lee S, Kim JY, Kang R, et al.

(18) Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcomaNature medicineFebruary 1, 2021Jerby-Arnon L, Neftel C, Shore ME, Weisman HR, Mathewson ND, McBride MJ, Haas B, Izar B, Volorio A, Boulay G, et al.236-EG-200), Recombinant Human FGF basic, 145 aa (TC Grade) Protein 10ng/mL (R&D systems, Cat. No. 4114-TC-01M) and 1% Penicillin-Streptomycin (Gibco, Cat. No. 15140122). Cells were expanded by mechanical and enzymatical

(19) SATB2 drives glioblastoma growth by recruiting CBP to promote FOXM1 expression in glioma stem cellsEMBO molecular medicineDecember 7, 2020Tao W, Zhang A, Zhai K, Huang Z, Huang H, Zhou W, Huang Q, Fang X, Prager BC, Wang X, et al.12587010), 10 ng/ml EGF(Gold biotechnology, Cat # 1150‐04‐1000), 10 ng/ml bFGF (R&D Systems, Cat # 4114‐TC‐01M), 2 mM l‐glutamine (Thermo Fisher, Cat # 35050061), and 1 mM sodium pyruvate (Thermo Fisher, Cat # 11360070)

(20) Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm StateCell stem cellNovember 5, 2020Zhang L, Avery J, Yin A, Singh AM, Cliff TS, Yin H, Dalton S.

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FGF basic/FGF2/bFGF (145 aa), Tissue Culture Grade Protein

FGF basic/FGF2/bFGF (145 aa), Tissue Culture Grade Protein from R&D Systems, a Bio-Techne Brand

Description

Specifications/Features

R&D Systems, a Bio-Techne Brand

Citations (42)

Reviews

FGF basic/FGF2/bFGF (145 aa), Tissue Culture Grade Protein from R&D Systems, a Bio-Techne Brand

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