Fig 2: Stable transfer characteristics (ID vs. VG at fixed VD = -0.3V) upon exposure to diluted human blood serum, as the baseline signal, and further exposed to human blood serum spiked with (a) KRAS and (b) MUC1 with concentrations ranging from 10 zM to 1 fM. (c) KRAS/b-KRAS dose–response curve (hollow red squares) are presented as the ?I/I0 vs. KRAS concentration. The negative control experiment towards KRAS with one mismatch is reported as hollow black squares. (d) MUC1/anti-MUC1 dose–response curve (hollow red squares) are presented as the ?I/I0 vs. MUC1 concentration. A BSA biofunctionalized gate was employed in the control experiment (hollow black squares). All the data points are provided as the average of at least three replicates, while the error bars were computed as the relative standard deviation, providing an estimation of the reproducibility of the assay