Native Clostridium difficile Toxin B protein ab124001 from Abcam

Product Specs
ItemNative Clostridium difficile Toxin B protein
CompanyAbcam
Price Supplier Page View Company Product Page
Catalog Numberab124001
FormatClostridium difficile Toxin B has been highly purified
Quantity50 UG
ApplicationsFuncS, SDS-PAGE
NCBI Gene AliasesCD0660, CD630DERM_06600
TypeNative
Gene NametoxB
Source/Expression SystemNative
ActivityActive
Molecule NameClostridium difficile Toxin B

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Abcam

Discovery Drive

Cambridge Biomedical Campus

Cambridge CB2 0AX

United Kingdom

Phone: +44 (0) 1223 696000 (option 1)
+44 (0) 1223 696000 (option 2)
+44 (0) 1223 771600

Company Profile

Website: http://www.abcam.com

(1) Steroid hormone catabolites activate the pyrin inflammasome through a non-canonical mechanismCell ReportsOctober 11, 2022Flora Magnotti, Daria Chirita, Sarah Dalmon, Amandine Martin, Pauline Bronnec, Jeremy Sousa, Olivier Helynck, Wonyong Lee, Daniel L. Kastner, Jae Jin Chae, et al.Chemicals. LPS-EB Ultrapure (#tlrl-3pelps), Nigericin (#tlrl-nig) were from Invivogen. TcdB was from Abcam (#ab124001). TcdA was purified from Clostridium difficile VPI10463 strain, as previously described (von Eichel-Streiber

(2) ASC deglutathionylation is a checkpoint for NLRP3 inflammasome activationThe Journal of experimental medicineSeptember 6, 2021Li S, Wang L, Xu Z, Huang Y, Xue R, Yue T, Xu L, Gong F, Bai S, Wu Q, et al.with 50 ng ml−1 LPS (Sigma-Aldrich, L4391) for 4 h and then stimulated with 500 ng ml−1 TcdB (Abcam, ab124001) for 1 h. Statistical analysis Statistical analyses were performed with Mann–Whitney U test, unpaired

(3) Pyrin dephosphorylation is sufficient to trigger inflammasome activation in familial Mediterranean fever patientsEMBO Molecular MedicineNovember 7, 2019Flora Magnotti et al.#4034771, #4027402, respectively), VX‐765 (InvivoGen), 30 min before addition of UCN‐01, TcdB (Abcam, #ab124001, 125 ng/ml), and TcdA (1 μg/ml) or nigericin. TcdA was purified from Clostridioides difficile VPI10463

(4) Lectin Activity of the TcdA and TcdB Toxins of Clostridium difficileInfection and ImmunityMarch 1, 2019Lauren E. Hartley-Tassell, Milena M. Awad, Kate L. Seib, Maria Scarselli, Silvana Savino, Joe Tiralongo, Dena Lyras, Christopher J. Day, Michael P. Jenningswere expressed and puriﬁed as previously described (22). Full-length TcdB was purchased from Abcam (ab124001). Glycan array. Glycans were prepared for printing as described by Day et al. (34). Glycan array slides were

(5) A novel Pyrin-Associated Autoinflammation with Neutrophilic Dermatosis mutation further defines 14-3-3 binding of pyrin and distinction to Familial Mediterranean FeverAnnals of the Rheumatic DiseasesDecember 1, 2017Fiona Moghaddas et al.Where indicated, cells were treated with Clostridium difficile Toxin B protein (TcdB, 5µg/ml, Abcam ab124001) 16h before harvesting. Cell lysates were generated 48h after transfection using 1% NP-40 lysis buffer

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Native Clostridium difficile Toxin B protein from Abcam

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Native Clostridium difficile Toxin B protein from Abcam

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