This application note explores the applications of the xCELLigence System for determining cell-mediated cytotoxicity, and specifically antibody-dependent cell-mediated cytotoxicity (ADCC). This is done by monitoring the response of tumor cells to natural killer cells in the presence or absence of immunoglobulin G isotype-specific antibody. Download this application note to read about the rationale for using these experimental parameters, the methods used, and the results of the study.
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