The development of animal models capable of mimicking human immune responses is crucial to study the pathophysiology of disease and to generate new therapeutic methodologies. Significant advances in immunology modeling have been made utilizing the super immune-deficient CIEA NOG mouse®, but the full application of engrafted human immune models depends upon overcoming some cross-species differences. Learn about key strains in the NOG Portfolio designed to overcome limitations in existing human immune system models.
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