Advances in clustered regularly interspaced short palindromic repeat (CRISPR) technology have led to the increased adoption of gene editing for applications ranging from understanding cell biology to treating diseases. Improvements in the speed, ease, accuracy, and efficiency of genome editing have also resulted in its successful use for screening, disease modeling, functional genomics, drug discovery and development

This Bench Tip webinar brings together a group of early-career scientists from labs that are actively working on optimizing and using various types of editing techniques—CRISPR editing, RNA editing, and base editing. They are keen to share best practices and technical know-how gained from many carefully designed and successfully executed experiments. Their short scientific presentations will be followed by a Q&A session to help the audience with their experiments.

In this webinar, you will learn about:

• Choosing the right reagents and design considerations
• Ensuring consistency of sample prep and experimental design for gene editing
• Optimizing editing workflows for specific applications
• Working with cell lines, 3D organoids, and in vivo models for editing
• Maximizing editing efficiency and minimizing off-target effects
• Case studies describing how editing can be used for various applications

• CRISPR screening
• RNA and base editing
• Genetic manipulations
• Disease modeling
• Gene expression profiling
• Functional genomics