For decades, scientists have debated whether the adult human brain can generate new neurons. The hippocampus has been at the heart of this uncertainty, with studies offering conflicting evidence. Now, researchers at the Karolinska Institutet have delivered compelling new data showing that neurogenesis continues into late adulthood. Using advanced techniques like single-nucleus RNA sequencing, spatial transcriptomics, and machine learning, they identified dividing neural progenitor cells in adult human brains. These findings provide strong evidence that the adult hippocampus retains its capacity to produce new neurons well beyond childhood.
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