Adenosine Deaminase Acting on RNA (ADAR) enzymes perform adenosine to inosine base editing in RNA, particularly targeting adenosines located within a specific double-stranded stem-loop motif.  ADAR1 plays important roles in inflammation, autoimmune diseases, and cancer, and represents an attractive target for therapeutic development.

BPS Bioscience has developed and validated high-throughput, cell-based assays for measuring ADAR1 editing activity.  This webinar will describe the principle of these cell-based assays, present data, and discuss the scientific applications of the cell lines.

You will learn about:

• The function of ADAR1
• How ADAR1 RNA-editing activity can be measured using a luciferase reporter system
• The research applications of ADAR1 reporter cell-based assays

• Drug discovery & development scientists
• Cell biologists
• RNA editing researchers
• Gene therapy researchers