ECSIT ELISA kits are immunoassay tools for the measurement of the protein ECSIT signaling integrator, which is encoded by the ECSIT gene in humans. Functionally, this protein is reported to be an adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1 and activation of IRF3/IRF7 pathways. The canonical protein structure is reported to have an amino acid length of 431 residues, a mass of 49.1 kDa, and is a member of the ECSIT protein family. It is known to be localized in the nucleus, mitochondria, and cytoplasm. As many as 4 protein isoforms have been reported. The ECSIT gene has been associated with the disease, . Other alias names for this target include evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial, ECSIT homolog, ECSIT signalling integrator, and SITPEC.
Some ECSIT ELISA kits can detect targets at levels as low as 78 pg/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.