The c-COT ELISA kits listed below utilize specific antibodies for the plate-based assay of c-COT in various samples. c-COT is another term for the MAP3K8 gene, which encodes the protein, mitogen-activated protein kinase kinase kinase 8 in humans. It has been reported that c-COT plays a role in the cell cycle and protein phosphorylation, among other functions. Structurally, the MAP3K8 protein is described to be 467 amino acid residues in length and 52.9 kilodaltons in mass. It is localized to the cytoplasm of the cell. In terms of tissue specificity, it is reported to be expressed in several normal tissues and human tumor-derived cell lines. This protein is known to be phosphorylated. Other names for this target antigen include AURA2, COT, and EST. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.