EIF2AK2 ELISA kits are immunoassay tools for the measurement of the protein eukaryotic translation initiation factor 2 alpha kinase 2, which is encoded by the EIF2AK2 gene in humans. Functionally, this protein is known to be involved in viral immune response and the regulation of apoptosis. The canonical protein structure is reported to have an amino acid length of 551 residues, a mass of 62.1 kDa, and is a member of the Ser/Thr protein kinase protein family. It is known to be localized in the nucleus and cytoplasm and is reported to be highly expressed in thymus, spleen and bone marrow compared to non-hematopoietic tissues such as small intestine, liver, or kidney tissues. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. The EIF2AK2 gene has been associated with the disease, Leukoencephalopathy, developmental delay, and episodic neurologic regression syndrome. Other alias names for this target include EIF2AK1, LEUDEN, PKR, PPP1R83, PRKR, and DYT33.
The detection range for different EIF2AK2 ELISA kits can vary, with some assays measuring target concentrations as low as 0.15 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.