LRP6 ELISA kits are immunoassay tools for the measurement of the protein LDL receptor related protein 6, which is encoded by the LRP6 gene in humans. Functionally, this protein is a known component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalosomes. The canonical protein structure is reported to have an amino acid length of 1613 residues, a mass of 180.4 kDa, and is a member of the LDLR protein family. It is known to be localized in the ER and cell membrane and is reported to be widely coexpressed with LRP5 during embryogenesis and in adult tissues. The protein has been noted to be post-translationally N-glycosylated, ubiquitinated, palmitoylated, cleaved and phosphorylated. The LRP6 gene has been associated with the disease, Coronary artery disease. Other alias names for this target include STHAG7, low-density lipoprotein receptor-related protein 6, and ADCAD2.
Some LRP6 ELISA kits can detect targets at levels as low as 62.5 pg/mL and as high as 50 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.