HGSNAT ELISA kits are immunoassay tools for the measurement of the protein heparan-alpha-glucosaminide N-acetyltransferase, which is encoded by the HGSNAT gene in humans. Functionally, this protein is reported to be a lysosomal acetyltransferase that acetylates the non-reducing terminal alpha-glucosamine residue of intralysosomal heparin or heparan sulfate, converting it into a substrate for luminal alpha-N-acetyl glucosaminidase. The canonical protein structure is reported to have an amino acid sequence of 663 residues and a mass of 73.3 kDa. It is known to be localized in the lysosomes and is found to be widely expressed, with highest level in leukocytes, heart, liver, skeletal muscle, lung, placenta and liver. The protein has been noted to be post-translationally glycosylated and cleaved. The HGSNAT gene has been associated with the disease, Mucopolysaccharidosis. Other alias names for this target include transmembrane protein 76.
Some HGSNAT ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.