CLN5 ELISA kits are immunoassay tools for the measurement of the protein CLN5 intracellular trafficking protein, which is encoded by the CLN5 gene in humans. Functionally, this protein is reported to play a role in in influencing the retrograde trafficking of lysosomal sorting receptors SORT1 and IGF2R from the endosomes to the trans-Golgi network by controlling the recruitment of retromer complex to the endosomal membrane. The canonical protein structure is reported to have an amino acid length of 358 residues, a mass of 41.5 kDa, and is a member of the CLN5 protein family. It is known to be localized in the lysosomes and is ubiquitously expressed across many tissue types. The protein has been noted to be post-translationally N-glycosylated and cleaved. The CLN5 gene has been associated with the disease, Ceroid lipofuscinosis. Other alias names for this target include ceroid-lipofuscinosis neuronal protein 5 and ceroid-lipofuscinosis, neuronal 5.
Some CLN5 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.