AAGAB ELISA kits are immunoassay tools for the measurement of the protein alpha and gamma adaptin binding protein, which is encoded by the AAGAB gene in humans. Functionally, this protein is suspected to be involved in endocytic recycling of growth factor receptors such as EGFR. The canonical protein structure is reported to have an amino acid sequence of 315 residues and a mass of 34.6 kDa. It is known to be localized in the cytoplasm and is reported to be widely expressed including in skin and keratinocytes, with highest levels in adrenal gland, rectum and thymus. As many as 2 protein isoforms have been reported. The AAGAB gene has been associated with the disease, Keratoderma. Other alias names for this target include alpha- and gamma-adaptin-binding protein p34 and punctate palmoplantar keratoderma type I.
The detection range for different AAGAB ELISA kits can vary, with some assays measuring target concentrations as low as 78 pg/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.