ATR ELISA kits are immunoassay tools for the measurement of the protein ATR serine/threonine kinase, which is encoded by the ATR gene in humans. Functionally, this protein is a serine/threonine protein kinase which activates checkpoint signaling upon genotoxic stresses such as ionizing radiation (IR), ultraviolet light (UV), or DNA replication stalling, thereby acting as a DNA damage sensor. The canonical protein structure is reported to have an amino acid length of 2644 residues, a mass of 301.4 kDa, and is a member of the PI3/PI4-kinase protein family. It is known to be localized in the nucleus and is found to be widely expressed, with highest expression in testis. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. The ATR gene has been associated with the disease, Seckel syndrome. Other alias names for this target include FRP1, MEC1, SCKL, SCKL1, serine/threonine-protein kinase ATR, and FCTCS.
There are ATR ELISA kits that can detect a target at concentrations as low as 0.312 ng/mL and as high as 40 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.