The TACE ELISA kits listed below utilize specific antibodies for the plate-based assay of TACE in various samples. TACE is another term for the ADAM17 gene, which encodes the protein, ADAM metallopeptidase domain 17 in humans. It has been reported that TACE plays a role in B cell differentiation and cell adhesion, among other functions. Structurally, the ADAM17 protein is 824 amino acid residues in length and 93 kilodaltons in mass. However, as many as 2 protein isoforms have been identified. It is localized to the membrane of the cell. In terms of tissue specificity, it is ubiquitously expressed across many tissue types. This protein is known to be glycosylated, cleaved and phosphorylated. Other names for this target antigen include ADAM18, CD156B, and CSVP.
The detection range for different TACE ELISA kits can vary, with some assays measuring target concentrations as low as 30 ng/L and as high as 20 ng/mL. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.