XPC ELISA kits are immunoassay tools for the measurement of the protein XPC complex subunit, DNA damage recognition and repair factor, which is encoded by the XPC gene in humans. Functionally, this protein is known to be involved in global genome nucleotide excision repair (GG-NER) by acting as damage sensing and DNA-binding factor component of the XPC complex. The canonical protein structure is reported to have an amino acid length of 940 residues, a mass of 106 kDa, and is a member of the XPC protein family. It is known to be localized in the nucleus and cytoplasm. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated and sumoylated. The XPC gene has been associated with the disease, Xeroderma pigmentosum. Other alias names for this target include XP3, XPCC, p125, DNA repair protein complementing XP-C cells, mutant xeroderma pigmentosum group C, and RAD4.
The detection range for different XPC ELISA kits can vary, with some assays measuring target concentrations as low as 13.7 pg/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.