BUB1 ELISA kits are immunoassay tools for the measurement of the protein BUB1 mitotic checkpoint serine/threonine kinase, which is encoded by the BUB1 gene in humans. Functionally, this protein is a type of serine/threonine-protein kinase that performs 2 crucial functions during mitosis: it is essential for spindle-assembly checkpoint signaling and for correct chromosome alignment. The canonical protein structure is reported to have an amino acid length of 1085 residues, a mass of 122.4 kDa, and is a member of the Ser/Thr protein kinase protein family. It is known to be localized in the nucleus and is reported be highly expressed in testis and thymus, less in colon, spleen, lung and small intestine. As many as 3 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated and phosphorylated. The BUB1 gene has been associated with the disease, Microcephaly. Other alias names for this target include BUB1L, MCPH30, hBUB1, mitotic checkpoint serine/threonine-protein kinase BUB1, and BUB1A. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.