RC3H2 ELISA kits are immunoassay tools for the measurement of the protein ring finger and CCCH-type domains 2, which is encoded by the RC3H2 gene in humans. Functionally, this protein is reported to be a post-transcriptional repressor of mRNAs containing a conserved stem loop motif, called constitutive decay element (CDE), which is often located in the 3'-UTR, as in HMGXB3, ICOS, IER3, NFKBID, NFKBIZ, PPP1R10, TNF and in many more mRNAs. The canonical protein structure is reported to have an amino acid sequence of 1191 residues and a mass of 131.7 kDa. It is known to be localized in the cytoplasm and is reported to be expressed in spleen, testis, ovary and small intestine. As many as 6 protein isoforms have been reported. The protein has been noted to be post-translationally cleaved. Other alias names for this target include RNF164, roquin-2, RING finger protein 164, RING-type E3 ubiquitin transferase Roquin-2, and MNAB.
The detection range for different RC3H2 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.