OGT ELISA kits are immunoassay tools for the measurement of the protein O-linked N-acetylglucosamine (GlcNAc) transferase, which is encoded by the OGT gene in humans. Functionally, this protein is known to catalyze the transfer of a single N-acetylglucosamine from UDP-GlcNAc to a serine or threonine residue in cytoplasmic and nuclear proteins resulting in their modification with a beta-linked N-acetylglucosamine (O-GlcNAc). The canonical protein structure is reported to have an amino acid length of 1046 residues, a mass of 116.9 kDa, and is a member of the Glycosyltransferase 41 protein family. It is known to be localized in the nucleus and cytoplasm and is reported to be highly expressed in pancreas and to a lesser extent in skeletal muscle, heart, brain and placenta. As many as 4 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated, ubiquitinated and phosphorylated. The OGT gene has been associated with the disease, Intellectual developmental disorder. Other alias names for this target include HRNT1, MRX106, O-GLCNAC, OGT1, XLID106, and HINCUT-1.
There are OGT ELISA kits that can detect a target at concentrations as low as 7.8 pg/mL and as high as 100 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.