The following Ataxin 1 ELISA kits are useful research tools for the measurement of ataxin 1 in biological samples. In humans this protein is encoded by the ATXN1 gene. This protein is reported to be a chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. The canonical protein structure is reported to have an amino acid length of 815 residues, a mass of 86.9 kDa, and is a member of the ATXN1 protein family. Its subcellular location is known to be in the nucleus and cytoplasm. In addition, it is reported to be widely expressed throughout the body. In certain instances, it is also post-translationally ubiquitinated, sumoylated and phosphorylated. The gene encoding this protein has been associated with the disease, Spinocerebellar ataxia. This protein may also be known as D6S504E, SCA1, alternative ataxin1, spinocerebellar ataxia type 1 protein, and ATX1.
There are ataxin 1 ELISA kits that can detect a target at concentrations as low as 15.625 pg/mL and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.