HDAC8 ELISA kits are immunoassay tools for the measurement of the protein histone deacetylase 8, which is encoded by the HDAC8 gene in humans. Functionally, this protein is reported to be a histone deacetylase that catalyzes the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). The canonical protein structure is reported to have an amino acid length of 377 residues, a mass of 41.8 kDa, and is a member of the Histone deacetylase protein family. It is known to be localized in the nucleus and cytoplasm and is reported to be weakly expressed in most tissues. As many as 6 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. The HDAC8 gene has been associated with the disease, Cornelia de Lange syndrome. Other alias names for this target include protein deacetylase HDAC8, protein decrotonylase HDAC8, and histone deacetylase-like 1.
Some HDAC8 ELISA kits can detect targets at levels as low as 0.06 ng/mL and as high as 50 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.