MADD ELISA kits are immunoassay tools for the measurement of the protein MAP kinase activating death domain, which is encoded by the MADD gene in humans. Functionally, this protein is known to be involved in receptor-mediated signaling pathways and the apoptotic pathway. The canonical protein structure is reported to have an amino acid length of 1647 residues, a mass of 183.3 kDa, and is a member of the MADD protein family. It is known to be localized in the cell membrane and cytoplasm and is reported to be expressed in testis, ovary, brain and heart. As many as 8 protein isoforms have been reported. The MADD gene has been associated with the disease, DEEAH syndrome. Other alias names for this target include DENN, IG20, NEDDISH, RAB3GEP, RabGEF, and DEEAH.
Some MADD ELISA kits can detect targets at levels as low as 15.625 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.