These ICE ELISA kits are immunodetection tools for measuring the levels of ICE in biological samples. ICE is an alias of the human CASP1 gene, which encodes the protein, caspase 1. Notably, ICE is known to play a role in the apoptotic pathway and the cellular response to lipopolysaccharides, among other functions. The CASP1 protein is 404 amino acid residues in length and 45.2 kilodaltons in mass. However, as many as 5 protein isoforms have been identified. It is localized to the cell membrane and cytoplasm of the cell. In terms of tissue specificity, it is reported to be expressed in larger amounts in spleen and lung. This protein is known to be ubiquitinated and cleaved. Other names for this target antigen include IL1BC. Click on the following ELISA kits for more detailed information, including target reactivity and assay sensitivity.