The following KIT proto-oncogene, receptor tyrosine kinase ELISA kits are useful research tools for the measurement of KIT proto-oncogene, receptor tyrosine kinase in biological samples. In humans this protein is encoded by the KIT gene. This protein is reported to be a tyrosine-protein kinase that acts as cell-surface receptor for the cytokine KITLG/SCF and plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. The canonical protein structure is reported to have an amino acid length of 976 residues, a mass of 109.9 kDa, and is a member of the Tyr protein kinase protein family. Its subcellular location is known to be in the cell membrane and cytoplasm. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally glycosylated, ubiquitinated and phosphorylated. The gene encoding this protein has been associated with the disease, Piebald trait. This protein may also be known as CD117, MASTC, PBT, SCFR, mast/stem cell growth factor receptor Kit, c-Kit protooncogene, p145 c-kit, and C-Kit.
The detection range for different KIT proto-oncogene, receptor tyrosine kinase ELISA kits can vary, with some assays measuring target concentrations as low as 0.97 pg/mL and as high as 100 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.