UBQLN4 ELISA kits are immunoassay tools for the measurement of the protein ubiquilin 4, which is encoded by the UBQLN4 gene in humans. Functionally, this protein is a reported regulator of protein degradation that mediates the proteasomal targeting of misfolded, mislocalized or accumulated proteins. The canonical protein structure is reported to have an amino acid sequence of 601 residues and a mass of 63.9 kDa. It is known to be localized in the nucleus, cytoplasmic vesicles, ER, and cytoplasm and is reported to be highly expressed in pancreas, kidney, skeletal muscle, heart and throughout the brain, and at lower levels in placenta, lung and liver. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally ubiquitinated and phosphorylated. The UBQLN4 gene has been associated with the disease, Amyotrophic lateral sclerosis. Other alias names for this target include ataxin-1 ubiquitin-like interacting protein, ataxin-1 ubiquitin-like-interacting protein A1U, connexin43-interacting protein of 75 kDa, and ataxin-1 interacting ubiquitin-like protein.
There are ubqln4 ELISA kits that can detect a target at concentrations as low as 0.1 ng/mL and as high as 40 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.