WASHC4 ELISA kits are immunoassay tools for the measurement of the protein WASH complex subunit 4, which is encoded by the WASHC4 gene in humans. Functionally, this protein is known to act as a component of the WASH core complex that functions as a nucleation-promoting factor (NPF) at the surface of endosomes, where it recruits and activates the Arp2/3 complex to induce actin polymerization, playing a key role in the fission of tubules that serve as transport intermediates during endosome sorting. The canonical protein structure is reported to have an amino acid length of 1173 residues, a mass of 136.4 kDa, and is a member of the CCDC53 protein family. It is known to be localized in the endosome. As many as 2 protein isoforms have been reported. The WASHC4 gene has been associated with the disease, Intellectual developmental disorder. Other alias names for this target include MRT43, SWIP, WASH complex subunit 7, WASH complex subunit SWIP, strumpellin and WASH-interacting protein, and KIAA1033.
There are WASHC4 ELISA kits that can detect a target at concentrations as low as 0.313 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.