PAK1 ELISA kits are immunoassay tools for the measurement of the protein p21 (RAC1) activated kinase 1, which is encoded by the PAK1 gene in humans. Functionally, this protein is known to be a protein kinase involved in intracellular signaling pathways downstream of integrins and receptor-type kinases that plays an important role in cytoskeleton dynamics, in cell adhesion, migration, proliferation, apoptosis, mitosis, and in vesicle-mediated transport processes. The canonical protein structure is reported to have an amino acid length of 545 residues, a mass of 60.6 kDa, and is a member of the STE Ser/Thr protein kinase protein family. It is known to be localized in the cytoplasm and is notably expressed in gastric cancer cells and tissues. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally phosphorylated. The PAK1 gene has been associated with the disease, Intellectual developmental disorder with macrocephaly, seizures, and speech delay. Other alias names for this target include PAKalpha, alpha-PAK, p65-PAK, serine/threonine-protein kinase PAK 1, STE20 homolog, yeast, and IDDMSSD.
Some PAK1 ELISA kits can detect targets at levels as low as 15.63 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.