LGI3 ELISA kits are immunoassay tools for the measurement of the protein leucine rich repeat LGI family member 3, which is encoded by the LGI3 gene in humans. Functionally, this protein is believed to participate in the regulation of neuronal exocytosis. The canonical protein structure is reported to have an amino acid sequence of 548 residues and a mass of 61.7 kDa. It is known to be localized in the cytoplasmic vesicles and is secreted and is found to be widely expressed, with highest levels in the brain and lung. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated. The LGI3 gene has been associated with the disease, Intellectual developmental disorder with muscle tone abnormalities and distal skeletal defects. Other alias names for this target include LGI1-like protein 4 and leucine-rich glioma-inactivated protein 3.
The detection range for different LGI3 ELISA kits can vary, with some assays measuring target concentrations as low as 20 ng/L and as high as 12 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.