EFEMP2 ELISA kits are immunoassay tools for the measurement of the protein EGF containing fibulin extracellular matrix protein 2, which is encoded by the EFEMP2 gene in humans. Functionally, this protein is reported to play a crucial role in elastic fiber formation in tissue, and in the formation of ultrastructural connections between elastic laminae and smooth muscle cells in the aorta, therefore participates in terminal differentiation and maturation of smooth muscle cell (SMC) and in the mechanical properties and wall integrity maintenance of the aorta. The canonical protein structure is reported to have an amino acid length of 443 residues, a mass of 49.4 kDa, and is a member of the Fibulin protein family. It is known to be localized in the extracellular matrix and is secreted. The protein has been noted to be post-translationally O-glycosylated, N-glycosylated and cleaved. The EFEMP2 gene has been associated with the disease, Cutis laxa. Other alias names for this target include FBLN4, MBP1, UPH1, EGF-containing fibulin-like extracellular matrix protein 2, EGF containing fibulin like extracellular matrix protein 2, and ARCL1B.
There are EFEMP2 ELISA kits that can detect a target at concentrations as low as 0.156 ng/mL and as high as 200 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.