APH1B ELISA kits are immunoassay tools for the measurement of the protein aph-1 homolog B, gamma-secretase subunit, which is encoded by the APH1B gene in humans. Functionally, this protein is a suspected subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (amyloid-beta precursor protein). The canonical protein structure is reported to have an amino acid length of 257 residues, a mass of 28.5 kDa, and is a member of the APH-1 protein family. It is known to be localized in the membrane. As many as 2 protein isoforms have been reported. Other alias names for this target include APH1B gamma secretase subunit, anterior pharynx defective 1 homolog B, and gamma-secretase subunit APH-1B.
The detection range for different APH1B ELISA kits can vary, with some assays measuring target concentrations as low as 7.8 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.