PLA2G6 ELISA kits are immunoassay tools for the measurement of the protein phospholipase A2 group VI, which is encoded by the PLA2G6 gene in humans. Functionally, this protein is known to be a calcium-independent phospholipase involved in phospholipid remodeling with implications in cellular membrane homeostasis, mitochondrial integrity and signal transduction. The canonical protein structure is reported to have an amino acid sequence of 806 residues and a mass of 89.9 kDa. It is known to be localized in the cell membrane, mitochondria, and cytoplasm. As many as 4 protein isoforms have been reported. The PLA2G6 gene has been associated with the disease, Neurodegeneration with brain iron accumulation. Other alias names for this target include GVI, INAD1, IPLA2-VIA, NBIA2, NBIA2A, NBIA2B, PARK14, and CaI-PLA2.
Some PLA2G6 ELISA kits can detect targets at levels as low as 31.25 pg/mL and as high as 40 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.