HLA-DRB1 ELISA kits are immunoassay tools for the measurement of the protein major histocompatibility complex, class II, DR beta 1, which is encoded by the HLA-DRB1 gene in humans. Functionally, this protein is known to be involved in epidermis development and immune response pathways. The canonical protein structure is reported to have an amino acid sequence of 266 residues and a mass of 30 kDa. It is known to be localized in the ER, lysosomes, and cell membrane and is reported to be expressed in professional APCs: monocyte/macrophages, dendritic cells and B cells. The protein has been noted to be post-translationally ubiquitinated and glycosylated. The HLA-DRB1 gene has been associated with the disease, Sarcoidosis. Other alias names for this target include HLA-DR1B, HLA-DRB, SS1, major histocompatibility complex, class II, DR beta 1 precursor, and DRB1.
There are HLA-DRB1 ELISA kits that can detect a target at concentrations as low as 39.06 pg/mL and as high as 50 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.