HARS1 ELISA kits are immunoassay tools for the measurement of the protein histidyl-tRNA synthetase 1, which is encoded by the HARS1 gene in humans. Functionally, this protein is known to catalyze the ATP-dependent ligation of histidine to the 3'-end of its cognate tRNA, via the formation of an aminoacyl-adenylate intermediate (His-AMP). The canonical protein structure is reported to have an amino acid length of 509 residues, a mass of 57.4 kDa, and is a member of the Class-II aminoacyl-tRNA synthetase protein family. It is known to be localized in the cytoplasm. As many as 4 protein isoforms have been reported. The HARS1 gene has been associated with the disease, Usher syndrome. Other alias names for this target include HARS, HRS, USH3B, histidine--tRNA ligase, cytoplasmic, HisRS, Jo-1 antigen, histidine translase, and CMT2W.
The detection range for different HARS1 ELISA kits can vary, with some assays measuring target concentrations as low as 15.6 pg/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.