RAB3GAP1 ELISA kits are immunoassay tools for the measurement of the protein RAB3 GTPase activating protein catalytic subunit 1, which is encoded by the RAB3GAP1 gene in humans. Functionally, this protein is a known catalytic subunit of the Rab3 GTPase-activating (Rab3GAP) complex composed of RAB3GAP1 and RAB3GAP2, which has GTPase-activating protein (GAP) activity towards various Rab3 subfamily members (RAB3A, RAB3B, RAB3C and RAB3D), RAB5A and RAB43, and guanine nucleotide exchange factor (GEF) activity towards RAB18. The canonical protein structure is reported to have an amino acid length of 981 residues, a mass of 110.5 kDa, and is a member of the Rab3-GAP catalytic subunit protein family. It is known to be localized in the ER and cytoplasm and is ubiquitously expressed across many tissue types. As many as 3 protein isoforms have been reported. The RAB3GAP1 gene has been associated with the disease, Warburg micro syndrome. Other alias names for this target include P130, RAB3GAP, RAB3GAP130, WARBM1, rab3 GTPase-activating protein catalytic subunit, and MARTS2.
Some RAB3GAP1 ELISA kits can detect targets at levels as low as 0.156 ng/mL and as high as 10 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.