APTX ELISA kits are immunoassay tools for the measurement of the protein aprataxin, which is encoded by the APTX gene in humans. Functionally, this protein is known to be a DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. The canonical protein structure is reported to have an amino acid sequence of 356 residues and a mass of 40.7 kDa. It is known to be localized in the nucleus and is reported to be widely expressed, detected in liver, kidney and lymph node. As many as 13 protein isoforms have been reported. The APTX gene has been associated with the disease, Ataxia-oculomotor apraxia syndrome. Other alias names for this target include AOA1, AXA1, EAOH, EOAHA, FHA-HIT, forkhead-associated domain histidine triad-like protein, and AOA.
Some APTX ELISA kits can detect targets at levels as low as 31.25 pg/mL and as high as 5000 pg/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.