ADAR ELISA kits are immunoassay tools for the measurement of the protein adenosine deaminase RNA specific, which is encoded by the ADAR gene in humans. Functionally, this protein is known to catalyze the hydrolytic deamination of adenosine to inosine in double-stranded RNA (dsRNA) referred to as A-to-I RNA editing. The canonical protein structure is reported to have an amino acid sequence of 1226 residues and a mass of 136.1 kDa. It is known to be localized in the nucleus and cytoplasm. As many as 5 protein isoforms have been reported. The protein has been noted to be post-translationally sumoylated. The ADAR gene has been associated with the disease, Dyschromatosis symmetrica hereditaria. Other alias names for this target include AGS6, DRADA, DSH, DSRAD, G1P1, IFI-4, IFI4, and ADAR1.
The detection range for different ADAR ELISA kits can vary, with some assays measuring target concentrations as low as 15 ng/L and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.