QTRT1 ELISA kits are immunoassay tools for the measurement of the protein queuine tRNA-ribosyltransferase catalytic subunit 1, which is encoded by the QTRT1 gene in humans. Functionally, this protein is a known catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). The canonical protein structure is reported to have an amino acid length of 403 residues, a mass of 44 kDa, and is a member of the Queuine tRNA-ribosyltransferase protein family. It is known to be localized in the membrane, mitochondria, and cytoplasm. As many as 2 protein isoforms have been reported. Other alias names for this target include TGT, catalytic subunit, guanine insertion enzyme, queuine tRNA-ribosyltransferase 1, tRNA-guanine transglycosylase, and TGT, 43-KD subunit.
There are QTRT1 ELISA kits that can detect a target at concentrations as low as 0.156 ng/mL and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.