The following Ataxin 3 ELISA kits are useful research tools for the measurement of ataxin 3 in biological samples. In humans this protein is encoded by the ATXN3 gene. This protein is known to be a deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded chaperone substrates. The canonical protein structure is reported to have an amino acid sequence of 361 residues and a mass of 41.3 kDa. Its subcellular location is known to be in the nucleus. In addition, it is ubiquitously expressed across many tissue types. As many as 5 protein isoforms have been reported. In certain instances, it is also post-translationally ubiquitinated. The gene encoding this protein has been associated with the disease, Spinocerebellar ataxia. This protein may also be known as ATX3, JOS, MJD, MJD1, SCA3, Machado-Joseph disease protein 1, josephin, and AT3.
The detection range for different ataxin 3 ELISA kits can vary, with some assays measuring target concentrations as low as 0.156 ng/mL and as high as 20 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.