Histamine ELISA kits are assays designed to detect the signaling molecule and neurotransmitter histamine, or alternatively, histamine receptors. Histamine plays a part in many processes, such as allergic modulation, inflammation, and gut regulation. It is stored largely in mast cells and basophils and acts by binding to receptors H1R- H4R. H1R and H4R are important as mediators of allergic diseases. H1R are expressed in many cells and are involved in Type 1 hypersensitivity reactions while H4R increases cytokine production. Visit the supplier page for more information about detection target, range, and reactivity.