The following Hemicentin 1 ELISA kits are useful research tools for the measurement of hemicentin 1 in biological samples. In humans this protein is encoded by the HMCN1 gene. This protein is known to be involved in transforming growth factor beta-mediated rearrangement of the podocyte cytoskeleton which includes reduction of F-actin fibers and broadening, flattening and elongation of podocytes. The canonical protein structure is reported to have an amino acid sequence of 5635 residues and a mass of 613.4 kDa. Its subcellular location is known to be in the extracellular matrix, cytoplasm, and is secreted. In addition, it is reported to be expressed in hair follicles and in the dermis. As many as 3 protein isoforms have been reported. In certain instances, it is also post-translationally glycosylated. The gene encoding this protein has been associated with the disease, Macular degeneration. This protein may also be known as LOC100507250/HMCN1 fusion and fibulin-6.
Some hemicentin 1 ELISA kits can detect targets at levels as low as 0.1 ng/mL and as high as 40 ng/mL. Use the search filters to narrow your search and click on the ELISA kits below for more detailed information, such as reactivity and assay sensitivity.