LIPA ELISA kits are immunoassay tools for the measurement of the protein lipase A, lysosomal acid type, which is encoded by the LIPA gene in humans. Functionally, this protein is known to catalyze the deacylation of triacylglyceryl and cholesteryl ester core lipids of endocytosed low density lipoproteins to generate free fatty acids and cholesterol. The canonical protein structure is reported to have an amino acid length of 399 residues, a mass of 45.4 kDa, and is a member of the Lipase protein family. It is known to be localized in the lysosomes. As many as 2 protein isoforms have been reported. The protein has been noted to be post-translationally glycosylated. The LIPA gene has been associated with the disease, Wolman disease. Other alias names for this target include LAL, lysosomal acid lipase/cholesteryl ester hydrolase, acid cholesteryl ester hydrolase, cholesterol ester hydrolase, and CESD.
The detection range for different LIPA ELISA kits can vary, with some assays measuring target concentrations as low as 15 ng/L and as high as 20 ng/mL. Click on the products below for more detailed ELISA kit information, such as target reactivity and assay sensitivity.