Anti-SP2 antibodies are used in the immunodetection of the protein Sp2 transcription factor. In humans, the canonical protein has a reported length of 613 amino acid residues and a mass of 64.9 kDa. Its subcellular localization is in the nucleus. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Sp1 C2H2-type zinc-finger protein family, Sp2 is known to bind to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. Synonyms for this target antigen include transcription factor Sp2. SP2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some Sp2 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.