Anti-Desmocollin 2 Antibody Products

Anti-Desmocollin 2 antibodies are used for the immunodetection of the protein encoded by the DSC2 gene. In humans, the canonical protein has a reported length of 901 amino acid residues and a mass of 100 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be expressed in the heart. It is known to be a component of intercellular desmosome junctions. Post-translational modifications have been described, including glycosylation.

The desmocollin 2 marker can be used to characterize Fibroblastic Reticular Cells (FRC).* Other names for this target antigen include CDHF2, DG2, DGII/III, DSC3, cadherin family member 2, desmosomal glycoprotein II/III, and ARVD11. Gene orthologs have been identified in the mouse, bovine and chimpanzee species. A number of Desmocollin 2 antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. ELISA and Western Blot are also common applications.