Anti-TRABD2B antibodies are used in the immunodetection of the protein TraB domain containing 2B. In humans, the canonical protein has a reported length of 517 amino acid residues and a mass of 57.4 kDa. Its subcellular localization is in the cell membrane. It is notably widely expressed in many tissue types. A member of the TIKI protein family, TRABD2B is a reported metalloprotease that acts as a negative regulator of the Wnt signaling pathway by mediating the cleavage of the 8 N-terminal residues of a subset of Wnt proteins. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include TRAB domain-containing protein 2B, UPF0632 protein A, heart, kidney and adipose-enriched transmembrane protein homolog, and metalloprotease TIKI2. TRABD2B gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. ELISA is a widely used application for the TRABD2B antibodies listed below. In addition, Western Blot is also a common application.