Anti-KLHL40 antibodies are used in the immunodetection of the protein kelch like family member 40. In humans, the canonical protein has a reported length of 621 amino acid residues and a mass of 69.3 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in fetal (19, 23 and 31 weeks of gestation) and adult skeletal muscle; expression levels tend to be higher in fetal compared to postnatal muscles. A member of the KLHL40 protein family, KLHL40 is reported to be a substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a key regulator of skeletal muscle development. The KLHL40 gene has been associated with the disease, Nemaline myopathy. Synonyms for this target antigen include kelch repeat and BTB (POZ) domain containing 5, kelch repeat and BTB domain-containing protein 5, nemaline myopathy type 8, sarcosynapsin, and kelch-like protein 40. Some KLHL40 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.