Anti-Exonuclease 1 antibodies are used for the immunodetection of the protein encoded by the EXO1 gene. In humans, the canonical protein has a reported length of 846 amino acid residues and a mass of 94.1 kDa. Its subcellular localization is in the nucleus. Alternative splicing is reported to yield 2 different isoforms for this protein. It is reported to be highly expressed in bone marrow, testis and thymus. A member of the XPG/RAD2 endonuclease protein family, it is known to be involved with DNA repair. Post-translational modifications have been described, including phosphorylation. Other names for this target antigen include hExoI, rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1, and HEX1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 70 citations in the literature describe the use of Exonuclease 1 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunofluorescence are also common applications.